All We Ask Is To Be Left Alone

ASK "to be, or not to be?".

“To be, or not to be? That is the question.” William Shakespeare, The Tragedy of Hamlet, Prince of Denmark (1599-1602). Viral infection triggers host defense mechanisms that include the production of type I interferon (IFN) and the induction of apoptosis. Type I IFN, such as IFN-α and IFN-β, establishes the antiviral state to inhibits viral replication within infected cells, whereas apoptosis o...

Should we all be vegetarians?

What We Need to Know About Responsiveness To Intervention (and Shouldn’t Be Afraid to Ask)

During the past several years, one of the most frequently addressed topics at conferences and in professional journals is responsiveness to intervention (RTI). This is because it is viewed by many as a new way to think about both early intervention and disability identification. Despite its relative newness, a subset of RTI proponents contend researchers and practitioners know everything they n...

Good science? We should all be asking

Objectivity is a central tenet of the scientific process. That is, in order for science to be a successful tool for understanding the nature of reality it must be free from bias. This idea is so core to science that cases of explicit bias (e.g., data fabrication and false reporting of results) are both mystifying and sensational. In principle and (we hope) in practice, instances of bias can be ...

Should we be giving enhanced vitamin D intakes to all?

It is widely established that vitamin D is critical for bone health. There is also an increasing body of evidence from observational studies that low levels of vitamin D are associated with a range of other disorders, including cancer and cardiovascular disease. People in temperate climates are often deficient in vitamin D, particularly in wintertime. The key question is whether there is suffic...